Study Of Macular Function and Morphology After Transepithelial Accelerated Corneal Collagen Cross-linking in Progressive Keratoconus

Objective The aim of this work is to evaluate the effect transepithelial accelerated cross-linking (Epi-on CXL) on macular function and morphology in progressive keratoconus. Patients Methods study included 25 patients with keratoconus age ranged between 18 32 years. Epi-On Accelerated CXL was done for all cases. Evaluation performed 2 6 weeks postoperatively after (Epi-on) by Optical coherence tomography (OCT) multifocal electroretinography (mf-ERG). Results central foveal thickness (CFT) decreased from 165.1 ± 21.5 µm 163.4 24.2 164.8 23.9 postoperatively, no statistically significant difference. preoperative retinal response density (RRD) ring 1 (foveal area 2.8 degrees) 179.5 52.1 nV/deg2 preoperatively 134.7 43.2 146.7 41.6 weeks, respectively difference (p = 0.012), while other 4 rings showed insignificant >0.05) .On hand, implicit time latency (Pl) postoperative values rings. Conclusion There a minimal change Epi-on keratoconus, however, without any structural changes postoperatively. A longer follow-up period studies are recommended provide more information.